Red and infrared light
Red and infrared light support mitochondrial function and skin resilience.
Strong consensus“the red spectrum of light penetrates into the mitochondria kicks nitric oxide off and then the electrons can flow through”
Metformin
The panel is split; metformin’s benefits for longevity are debated and support is thin so far.
Genuinely contestedFor longevity and mitochondrial medicine.
Both sides, in their own words
Our sources differ. Compare their views and the context behind each one.
One side
“I'm not gonna lie to him and tell them that taking metformin or or you know using melitan on their skin or you know some MLM marketing scheme is the way to go that's it's total”
a molecular biology PhD · source video · 00:14:32
The other
“Both inhibit complex one of the respiratory chain and can exacerbate symptoms severely”
a nutritional sciences PhD · source video · 00:01:40
In their own words
One faithful sentence per source, linked to the moment it was said; quiet chips mark where money is involved.
a nutritional sciences PhD against
“Both inhibit complex one of the respiratory chain and can exacerbate symptoms severely”
a nutritional sciences PhD · source video · 00:01:40
a board-certified cardiologist conditional
“If lifestyle alone does not reduce visceral fat, medications such as metformin may have benefit.”
a board-certified cardiologist · source video · 00:03:20
a former research biochemist recommend
“Some drugs have positives that generally outweigh negatives and can fill gaps in treatment when combined with diet and lifestyle.”
a former research biochemist · Instagram reel sponsored
a Harvard-trained gynecologist conditional
“Metformin, a diabetic medication, is becoming popular for anti-aging but is not universally recommended yet.”
a Harvard-trained gynecologist · source video · 00:10:10
a registered nutritional therapist recommend
“Metformin depletes vitamin B12 and folate leading to symptoms like numbness and fatigue.”
a registered nutritional therapist · Instagram reel
a molecular biology PhD neutral
“Studies show metformin with aerobic exercise undid insulin sensitivity and mitochondrial benefits and decreased muscle gain with strength training.”
a molecular biology PhD · TikTok video
Worth discussing with your GP, especially if you take medication or are pregnant. Entrain describes what is publicly taught; it does not prescribe.
The research our sources reach for
Peer-reviewed papers cited alongside this verdict, linked straight to PubMed.
On 5 September 2026, 340 studies in the library were compared by identifier with 72,389 Retraction Watch entries. No matching notices were found. This check does not establish study quality or validate a health claim.
More from mitochondria
Infrared light therapy
Infrared light therapy is widely valued for supporting mitochondria and relaxation.
Strong consensus“infrared light which can penetrate 8cm into the body can help to clear this out of the way so that your mitochondria can carry on making ATP and water”
Infrared exposure
Infrared exposure helps support healthy blood flow and cellular energy production.
Strong consensus“The main things are sunlight exposure, infrared light, anything that's going to build charge in your body is going to help build the structured water and that’s going to prevent this clotting response.”